Herman J B, Medalie J H, Goldbourt U
Diabetologia. 1977 May;13(3):229-34. doi: 10.1007/BF01219704.
498 diabetics were discovered in a survey of ischaemic heart disease in 10,059 men aged 40 years and over in Israel. -The diabetics were divided into previously known and newly diagnosed. -During a 5 year follow-up period, the incidence rates of fatal and non-fatal myocardial infarction and the incidence of intermittent claudication were considerably greater in both groups of diabetics than in non-diabetics. The frequency of hypertension and left ventricular hypertrophy was about the same in both groups, and in non-diabetics. -However, the pattern of increased morbidity for angina pectoris and the increased rate of sudden death is seen only in the previously diagnosed diabetics. Different pathological mechanisms might be responsible for angina pectoris and sudden death, as compared to myocardial infarction and these might be related in diabetics to the duration and severity of the disease.
在对以色列10059名40岁及以上男性进行的缺血性心脏病调查中，发现了498名糖尿病患者。糖尿病患者被分为既往已知病例和新诊断病例。在5年的随访期内，两组糖尿病患者的致命性和非致命性心肌梗死发病率以及间歇性跛行发病率均显著高于非糖尿病患者。两组糖尿病患者以及非糖尿病患者的高血压和左心室肥厚发生率大致相同。然而，心绞痛发病率增加和猝死率上升的情况仅在既往诊断的糖尿病患者中出现。与心肌梗死相比，心绞痛和猝死可能由不同的病理机制所致，而在糖尿病患者中，这些机制可能与疾病的持续时间和严重程度有关。
