Opalchenova G, Dyulgerova E, Petrov O E
National Drug Institute, Sofia, Bulgaria.
J Biomed Mater Res. 1996 Jun;31(2):219-26. doi: 10.1002/(SICI)1097-4636(199606)31:2<219::AID-JBM8>3.0.CO;2-Q.
An in vitro study of the influence of Biphase Calcium Phosphate Ceramics (BCPCs) on bacterial strains is presented. The test procedures were carried out in saline test solution to which different quantities (2,4,50,100, and 200 mg) of BCPCs(samples A and B) were added. The influence of BCPCs on standard bacterial strains has been determined by measuring bacterial contamination using the plate count method. The testing method was validated with membrane filtration and direct inoculation in culture media of sediment and supernatant. The test demonstrated reduction of the bacterial cell population in from 1 to 24 h in all experiments. The antibacterial effect revealed the specific inherent properties of the BCPCs under investigation.
本文介绍了双相磷酸钙陶瓷（BCPCs）对细菌菌株影响的体外研究。测试程序在盐溶液测试中进行，向其中添加了不同量（2、4、50、100和200毫克）的BCPCs（样品A和B）。通过平板计数法测量细菌污染来确定BCPCs对标准细菌菌株的影响。该测试方法通过膜过滤以及沉积物和上清液在培养基中的直接接种进行了验证。测试表明，在所有实验中，细菌细胞数量在1至24小时内有所减少。抗菌效果揭示了所研究的BCPCs的特定固有特性。
