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[牛截瘫综合征中的骨骼肌超微结构病理学]

[Skeletal muscle ultrastructural pathology in bovine paraplegic syndrome].

作者信息

Medina de López N, Finol H J, Marín C

机构信息

Instituto de Investigaciones Veterinarias, Aragua, Venezuela.

出版信息

Acta Cient Venez. 1994;45(2):120-6.

PMID:8731296
Abstract

This study reports the ultrastructural alterations found in biopsies taken from fast twitch gastrocnemius and slow twitch soleus muscles from bovines affected by the paraplegic syndrome. The abnormalities observed were contractile and sarcotubular systems disorganization, proliferation of autophagic vacuoles with mitochondrial material and glycogenosomes, decrease of nuclear chromatin electron density, and sacrolemmal damage in areas of segmental necrosis where macrophages were also seen. Capillary alterations were slight. Mentioned abnormalities are discussed in connection with mineral nutritional deficiences presented by the studied animals.

摘要

本研究报告了从患有截瘫综合征的牛的快肌腓肠肌和慢肌比目鱼肌活检样本中发现的超微结构改变。观察到的异常包括收缩和肌管系统紊乱、含有线粒体物质和糖原小体的自噬泡增殖、核染色质电子密度降低以及节段性坏死区域的肌膜损伤,在这些区域还可见巨噬细胞。毛细血管改变轻微。结合所研究动物出现的矿物质营养缺乏情况对上述异常进行了讨论。

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