Rios A C, Cavalcanti S M, Menezes D M, Oliveira L H
Departamento de Microbiologia e Parasitologia, Universidade Federal Fluminense, Niterói.
Rev Assoc Med Bras (1992). 1995 Sep-Oct;41(5):333-6.
In order to investigate genital papillomavirus infection in a university hospital, we verified that condyloma acuminata and epidermoid carcinoma were the most common diseases associated to this virus.
This study was undertaken to verify the prevalence of genital lesions associated to papillomavirus and sex, age and race distribution.
We have reported 223 patients who were treated at Hospital Universitario Antonio Pedro, Rio de Janeiro State, during the period 1988-1992. After clinical diagnosis, biopsies were submitted to histological analysis.
Results showed that condyloma acuminata and epidermoid carcinoma were the most frequent lesions among genital lesions. Carcinoma cases had a stable prevalence along the period while condyloma cases had a significant increase. Both lesions were more frequently found in Caucasian (white) patients. There were no differences between sexes and condyloma evidence. The media age in the epidermoid carcinoma cases did not change in the years, but it has decreased regarding condyloma acuminata.
Genital diseases associated to papillomavirus increased during five years. Attention must be paid to control and early diagnosis to prevent neoplasic evolution.
为了调查一所大学医院中的人乳头瘤病毒感染情况，我们证实尖锐湿疣和表皮样癌是与该病毒相关的最常见疾病。
本研究旨在证实与人乳头瘤病毒相关的生殖器病变的患病率以及性别、年龄和种族分布情况。
我们报告了1988年至1992年期间在里约热内卢州安东尼奥·佩德罗大学医院接受治疗的223例患者。临床诊断后，对活检组织进行组织学分析。
结果显示，尖锐湿疣和表皮样癌是生殖器病变中最常见的病变。在此期间，癌病例的患病率稳定，而尖锐湿疣病例显著增加。两种病变在白种人（白人）患者中更为常见。性别与尖锐湿疣的发病情况之间没有差异。表皮样癌病例的平均年龄在这些年中没有变化，但尖锐湿疣的平均年龄有所下降。
与人乳头瘤病毒相关的生殖器疾病在五年间有所增加。必须重视控制和早期诊断，以预防肿瘤进展。
