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[应用大分子透明质酸钠预防屈指肌腱粘连的实验研究]

[Experimental research on using macromolecule sodium hyaluronate to prevent flexior tendon adhesion].

作者信息

Chen Z, Gu J

机构信息

People's Liberation Army Air Force, Shanghai First Hospital.

出版信息

Zhonghua Wai Ke Za Zhi. 1995 Sep;33(9):526-8.

PMID:8731868
Abstract

With chicken paw as an animal model, we studied the effects of sodium hyaluronate product (SHP) on the heal of injured tendon and the formation of post-surgical tendon adhesions. The function of digit flexion angle and moving function of the tendon in SHP group were remarkably superior to those of tendons in physiological salt solution control group (P < 0.01). Tendons of the experiment group healed well, their surface was smooth without adhesion. False sheath was formed around the tendon, and there was also a gap between the false sheath and the tendon. However, the adhesion between the tendon and its surrounding tissue in the control group was donse with clear boundary. These results suggest that SHP has a protective effect against the formation of adhesion in healing tendon.

摘要

以鸡爪为动物模型,我们研究了透明质酸钠产品(SHP)对损伤肌腱愈合及术后肌腱粘连形成的影响。SHP组的手指屈曲角度功能和肌腱活动功能明显优于生理盐水对照组的肌腱(P<0.01)。实验组肌腱愈合良好,表面光滑无粘连。肌腱周围形成了假鞘,且假鞘与肌腱之间也存在间隙。然而,对照组中肌腱与其周围组织之间的粘连紧密,边界清晰。这些结果表明,SHP对愈合过程中肌腱粘连的形成具有保护作用。

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1
[Experimental research on using macromolecule sodium hyaluronate to prevent flexior tendon adhesion].[应用大分子透明质酸钠预防屈指肌腱粘连的实验研究]
Zhonghua Wai Ke Za Zhi. 1995 Sep;33(9):526-8.
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[Experimental study of sodium hyaluronate products on prevention of tendon adhesion].透明质酸钠产品预防肌腱粘连的实验研究
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Mixture of hyaluronic acid and phospholipid prevents adhesion formation on the injured flexor tendon in rabbits.
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Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2007 Aug;21(8):842-6.
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Effects of hydroxyapatite and alumina sheaths on postoperative peritendinous adhesions in chickens.羟基磷灰石和氧化铝鞘对鸡术后肌腱周围粘连的影响。
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