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透明质酸钠产品预防肌腱粘连的实验研究

[Experimental study of sodium hyaluronate products on prevention of tendon adhesion].

作者信息

Xu J, Gu Y, Wang H

机构信息

Department of Hand Surgery, Hua Shan Hospital, Shanghai Medical University.

出版信息

Zhonghua Wai Ke Za Zhi. 1995 Sep;33(9):529-31.

PMID:8731869
Abstract

In an experiment sodium hyaluronate product (SHP) was used to observe its effects on healing and preventing adhesion of rabbit muscle tendon. Several methods were used such as gross and histopathological observation, imaging analysis, anti-tension strength measurement. The results confirmed that SHP could reduce collagen contents in peri-tendon tissues and fibroblasts after surgery and decrease the formation of scars in peri-tendon tissues. Therefore, it is effective in preventing muscle tendon adhesion and improving slide function of muscle tendon. Besides, it does not hinder muscle tendon healing.

摘要

在一项实验中,使用了透明质酸钠产品(SHP)来观察其对兔肌腱愈合和预防粘连的影响。采用了多种方法,如大体和组织病理学观察、影像学分析、抗张强度测量。结果证实,SHP可降低术后肌腱周围组织中的胶原蛋白含量和成纤维细胞数量,并减少肌腱周围组织中的瘢痕形成。因此,它在预防肌腱粘连和改善肌腱滑动功能方面是有效的。此外,它不会妨碍肌腱愈合。

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