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[肾上腺皮质癌:20例报告]

[Adrenocortical carcinoma: report of 20 cases].

作者信息

Jiang W, Yang G, Wei W

机构信息

Department of Urology, Affiliated Union Hospital, Fujian Medical College, Fuzhou.

出版信息

Zhonghua Wai Ke Za Zhi. 1995 Oct;33(10):621-2.

PMID:8731899
Abstract

The authors reported 20 cases of adrenocortical corcinoma. The tumors were nonfunctional in 12 cases (average age 49.7) and functional in 8 cases (5 with hypercortisolism, 3 with adrenogenital syndrome; average age 8.8). The prognosis in this group were poor, the survival of one year was 40%, two years 35% and five years 10%. Most of adrenocortical carcinomas in childhood were functional and their prognosis were poor because of delayed treatment. The nonfunctional tumors were usually diagnosed in the late period, therefore the prognosis was worse, but in recent years some cases of no secretory carcinomas had been occasionally found by image diagnosis and these tumors were small, so their prognosis was favorate.

摘要

作者报告了20例肾上腺皮质癌。12例肿瘤无功能(平均年龄49.7岁),8例有功能(5例为皮质醇增多症,3例为肾上腺性征异常综合征;平均年龄8.8岁)。该组预后较差,1年生存率为40%,2年生存率为35%,5年生存率为10%。儿童期的肾上腺皮质癌大多有功能,且由于治疗延迟,其预后较差。无功能肿瘤通常在晚期才被诊断出来,因此预后更差,但近年来通过影像诊断偶尔发现了一些无分泌功能的癌,这些肿瘤较小,所以其预后较好。

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