Mahmood T, Silverstone T, Spittle B
Wakari Hospital, Dunedin School of Medicine, University of Otago Medical School, New Zealand.
Int Clin Psychopharmacol. 1996 Mar;11(1):53-4. doi: 10.1097/00004850-199603000-00007.
Two cases are reported who developed blood dyscrasias, involving neutropenia and thrombocytopenia respectively, after treatment with phenothiazine and butyrophenone antipsychotics. A subsequent good therapeutic response was obtained with risperidone. It is suggested that risperidone may be considered as an alternative when blood dyscrasias occur with classic antipsychotics.
报告了两例患者，他们在使用吩噻嗪类和丁酰苯类抗精神病药物治疗后分别出现了血液系统异常，涉及中性粒细胞减少和血小板减少。随后使用利培酮获得了良好的治疗反应。建议当经典抗精神病药物出现血液系统异常时，可考虑将利培酮作为替代药物。
