Klijanienko J, Vielh P
Départment de Pathologie, Institut Curie, Paris, France.
Diagn Cytopathol. 1996 May;14(3):195-200. doi: 10.1002/(SICI)1097-0339(199604)14:3<195::AID-DC1>3.0.CO;2-H.
Fine-needle sampling (FNS) of 412 pleomorphic adenomas, corresponding to 378 primary tumors and 34 local recurrences, was performed preoperatively in 378 patients. Concordant cytologic diagnoses were established in 376 tumors (91.3%), whereas seven (1.7%) were only classified as benign. Sixteen (3.9%) tumors were considered to be suspicious and two (0.5%) were diagnosed as adenoid cystic carcinomas. Insufficient material for cytologic evaluation was found in 11 (2.6%) tumors. Pleomorphic adenomas were retrospectively classified according to the predominant histological differentiation: chondromyxoid, cellular, myoepithelial, or metaplastic. FNS performances were higher in chondromyxoid than in other types, with 95.2% concordant and 1.4% suspicious/ false-positive, vs. 81.8% concordant, and 11.5% suspicious/false-positive cytodiagnoses, respectively.
对412例多形性腺瘤进行细针采样（FNS），其中包括378例原发性肿瘤和34例局部复发肿瘤，术前对378例患者进行了采样。376例肿瘤（91.3%）建立了一致的细胞学诊断，而7例（1.7%）仅被分类为良性。16例（3.9%）肿瘤被认为可疑，2例（0.5%）被诊断为腺样囊性癌。11例（2.6%）肿瘤发现细胞学评估材料不足。多形性腺瘤根据主要组织学分化进行回顾性分类：软骨黏液样、细胞性、肌上皮性或化生型。软骨黏液样型的FNS诊断效能高于其他类型，一致诊断率为95.2%，可疑/假阳性率为1.4%，而其他类型的一致诊断率分别为81.8%，可疑/假阳性率为11.5%。
