Lebet J P, Barbault A, Rossel C, Tomic Z, Reite M, Higgs L, Dafni U, Amato D, Pasche B
Symtonic SA., Renens, Switzerland.
Ann Biomed Eng. 1996 May-Jun;24(3):424-9. doi: 10.1007/BF02660891.
Low energy emission therapy (LEET) is a novel approach to delivering low levels of amplitude-modulated electromagnetic fields to the human brain. The sleep electroencephalogram (EEG) effects of a 15-min LEET treatment were investigated in a double-find cross-over study to assess sleep induction. Fifty-two healthy volunteers were exposed to both active and inactive LEET treatment sessions, with a minimum interval of 1 week between the two sessions. Baseline EEGs were obtained, and 15-min posttreatment EEGs were recorded and analyzed according to the Loomis classification. A significant increase in the duration of stage B1 sleep (0.58 +/- 2.42 min [mean +/- SD], p = 0.046), decreased latency to the first 10 sec epoch of sleep (-1.23 +/- 5.32 min, p = 0.051) and decreased latency to sleep stage B2 (-1.21 +/- 5.25 min, p = 0.052) were observed after active treatment. Additionally, establishment of slow waves with progression from stages B to C was significantly more pronounced after active LEET treatment (p = 0.040). A combined analysis of these results with those of an identical study performed in Denver showed that LEET had a significant effect on afternoon sleep induction and maintenance with shorter sleep latencies (decreased latency to the first 10 sec epoch of sleep; -1.00 +/- 5.51 min, p = 0.033; decreased latency to sleep stage B2; -1.49 +/- 5.40 min, p = 0.003), an increased duration of stage B2 (0.67 +/- 2.50 min, p = 0.003), an increase in the total duration of sleep (0.69 +/- 4.21 min, p = 0.049), and a more prominent establishment of slow waves with progression to a deeper sleep stage (p = 0.006). It is concluded that the intermittent 42.7 HZ amplitude modulation of 27.12-MHz electromagnetic fields results in EEG changes consistent with shorter sleep latencies, longer sleep duration, and deeper sleep in healthy subjects.
低能量发射疗法（LEET）是一种向人脑中传递低水平调幅电磁场的新方法。在一项双盲交叉研究中，研究了15分钟LEET治疗对睡眠脑电图（EEG）的影响，以评估睡眠诱导作用。52名健康志愿者分别接受了有源和无源LEET治疗，两次治疗之间的间隔至少为1周。记录了基线脑电图，并根据卢米斯分类法对治疗后15分钟的脑电图进行了记录和分析。有源治疗后，观察到B1期睡眠持续时间显著增加（0.58±2.42分钟[平均值±标准差]，p = 0.046），首次出现10秒睡眠期的潜伏期缩短（-1.23±5.32分钟，p = 0.051），以及进入B2期睡眠的潜伏期缩短（-1.21±5.25分钟，p = 0.052）。此外，有源LEET治疗后，从B期到C期慢波的形成明显更显著（p = 0.040）。将这些结果与在丹佛进行的一项相同研究的结果进行综合分析表明，LEET对下午的睡眠诱导和维持有显著影响，睡眠潜伏期更短（首次出现10秒睡眠期的潜伏期缩短；-1.00±5.51分钟，p = 0.033；进入B2期睡眠的潜伏期缩短；-1.49±5.40分钟，p = 0.003），B2期持续时间增加（0.67±2.50分钟，p = 0.003），总睡眠时间增加（0.69±4.21分钟，p = 0.049），并且随着进入更深睡眠阶段，慢波的形成更显著（p = 0.006）。得出的结论是，27.12 MHz电磁场的间歇性42.7 Hz调幅导致脑电图变化，与健康受试者更短的睡眠潜伏期、更长的睡眠时间和更深的睡眠一致。
