[与2型抗线粒体抗体相关的关节及全身表现]
[Joint and systemic manifestations related to type 2 anti-mitochondrial antibodies].
作者信息
Dhôte R, Christoforov B, Weill B, Menkes C J
机构信息
Service de Médecine Interne, Hôpital Cochin, Paris.
出版信息
Ann Med Interne (Paris). 1995;146(8):536-40.
The aim of the study was to assess the significance of type 2 anti-mitochondrial antibodies in patients with systemic and inflammatory rheumatic disease. Articular and systemic manifestations of 8 patients associated with type 2 anti-mitochondrial antibodies are described. All the patients had hepatic abnormalities, and 5 of them disclosed a primary biliary cirrhosis. Articular and systemic manifestations were similar to those observed in primary biliary cirrhosis. Therefore, the finding of anti-mitochondrial antibodies in patients with systemic or inflammatory rheumatic disease implies research for other systemic manifestations such as primary biliary cirrhosis.
该研究的目的是评估2型抗线粒体抗体在系统性和炎性风湿性疾病患者中的意义。描述了8例与2型抗线粒体抗体相关患者的关节和全身表现。所有患者均有肝脏异常，其中5例诊断为原发性胆汁性肝硬化。关节和全身表现与原发性胆汁性肝硬化中观察到的相似。因此，在系统性或炎性风湿性疾病患者中发现抗线粒体抗体意味着要对其他全身表现如原发性胆汁性肝硬化进行研究。
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