Fontaine G, Frank R, Gallais Y, Rosás Andrade F, Tonet J, Lascault G, Aouate P, Poulain F
Service de rythmologie et de stimulation cardiaque, hôpital Jean-Rostand, Ivry-sur-Seine.
Arch Mal Coeur Vaiss. 1996 Feb;89 Spec No 1:99-107.
Radiofrequency energy was used for the ablation of chronic recurrent ventricular tachycardia (VT) in 58 patients who were divided into two groups: 44 cases with structural myocardial disease (36 men and 8 women: mean age 55 years; range: 14 to 85 years) with an average left ventricular ejection fraction of 38% (range: 15 to 80%): these patients had myocardial infarction (28 cases), arrhythmogenic right ventricular dysplasia (11 cases), idiopathic dilated cardiomyopathy (2 cases), operated congenital heart disease (2 cases) and operated valvular heart disease (1 case). The clinical success rate after the first session of radiofrequency ablation was 34%. When (according to our modified protocol of fulguration) 160 joule cathodal shocks were delivered to the same catheter previously used for RF ablation during the same session or secondarily (13 cases), the success rate increased to 76%. The average follow-up period of the 37 survivors was 16.7 months. The second group consists of 14 cases without structural myocardial disease (10 men and 4 women, mean age 41 years, range 14 to 69 years) with an average left ventricular ejection fraction of 61%. These patients had idiopathic ventricular tachycardia (10 cases) and verapamil-sensitive ventricular tachycardia (4 cases). The primary success of radiofrequency ablation alone was 43%. When combined with fulguration during the same of radiofrequency ablation alone was 43%. When combined fulguration during the same of at a later session, the success rate increased to 71.3%. The average follow-up period of the 13 survivors was 19 months (range 0.3 to 39 months). No significant difference was observed between the groups with or without structural myocardial disease after radiofrequency or fulguration ablation, not only with respect to global results but also after analysis of subgroups with, for example, post-infarction ventricular tachycardia or arrhythmogenic right ventricular dysplasia. However, clinical success was obtained after a single session of radiofrequency ablation alone in 8 of the 9 cases of incessant ventricular tachycardia in patients with structural myocardial disease.
58例慢性复发性室性心动过速(VT)患者接受了射频能量消融治疗,这些患者被分为两组:44例患有结构性心肌病(36例男性和8例女性,平均年龄55岁,范围:14至85岁),平均左心室射血分数为38%(范围:15至80%):这些患者患有心肌梗死(28例)、致心律失常性右心室发育不良(11例)、特发性扩张型心肌病(2例)、先天性心脏病手术后(2例)和心脏瓣膜病手术后(1例)。首次射频消融术后的临床成功率为34%。当(根据我们改良的电灼方案)在同一次或第二次手术中向先前用于射频消融的同一导管施加160焦耳的阴极电击时(13例),成功率提高到76%。37名幸存者的平均随访期为16.7个月。第二组由14例无结构性心肌病的患者组成(10例男性和4例女性,平均年龄41岁,范围14至69岁),平均左心室射血分数为61%。这些患者患有特发性室性心动过速(10例)和维拉帕米敏感性室性心动过速(4例)。单独射频消融的初次成功率为43%。当在同一次或稍后的手术中与电灼联合使用时,成功率提高到71.3%。13名幸存者的平均随访期为19个月(范围0.3至39个月)。在射频或电灼消融后,有或无结构性心肌病的组之间未观察到显著差异,不仅在总体结果方面,而且在对例如心肌梗死后室性心动过速或致心律失常性右心室发育不良等亚组进行分析后也是如此。然而,在结构性心肌病患者的9例持续性室性心动过速中,有8例仅通过单次射频消融就获得了临床成功。