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鼻窦毛霉菌病

Mucormycosis of the paranasal sinuses.

作者信息

Perolada Valmana J M, Morera Perez C, Blanes Julia M, Casanova Estruch B, Beaus Climent B

机构信息

Servicio de Otorrinolaringologia, Hospital Universitario La Fe, Valencia, España.

出版信息

Rev Laryngol Otol Rhinol (Bord). 1996;117(1):51-2.

PMID:8734266
Abstract

Between 1989 and 1992 we had two cases of mucormycosis. The first patient presented with left hemiplegia: radiologic studies showed a right sphenoidal sinus mass, cerebral ischaemic infarction and occlusion of the right carotid artery. The second patient was seen with an abscess of the hard palate after long term steroid therapy. CT scan showed a soft-tissue mass occupying the maxillary sinus, which had eroded its walls and spread to palate, orbit and ethmoidal cells. We have emphasised the presence of hyperglycemia in both cases, the marked tendency of this lesion to invade blood vessels, and the good results obtained by combining liposomal amphotericin B with radical surgical debridement.

摘要

1989年至1992年间,我们遇到了两例毛霉菌病患者。首例患者表现为左侧偏瘫:影像学检查显示右侧蝶窦肿块、脑、脑缺血性梗死以及右侧颈动脉闭塞。第二例患者在长期接受类固醇治疗后出现硬腭脓肿。CT扫描显示一个软组织肿块占据上颌窦,该肿块已侵蚀其壁并蔓延至腭部、眼眶和筛窦小房。我们强调了这两例患者均存在高血糖情况,该病变显著的血管侵袭倾向,以及脂质体两性霉素B联合根治性手术清创所取得的良好效果。

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