Eubanks L E, McBurney E I, Galen W, Reed R
Department of Dermatology, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Int J Dermatol. 1996 May;35(5):330-6. doi: 10.1111/j.1365-4362.1996.tb03633.x.
Linear scleroderma is a cutaneous disease of unknown etiology. It most often affects children, who develop band-like lesions in an asymmetric distribution. The literature is reviewed as to the diagnosis, pathogenesis, and treatment of linear scleroderma.
Six new cases of linear scleroderma in children are reported. Their ages ranged from 6 to 17 years, and five were girls. A 17-year-old girl had en coup de sabre. Multiple treatment modalities were used. All laboratory testing was negative.
Linear scleroderma is a clinical diagnosis. The pathogenesis remains unknown. A consistently effective therapy has not been found, although diphenylhydantoin and ticlopidine hydrochloride should be evaluated in clinical trials.
线状硬皮病是一种病因不明的皮肤病。它最常影响儿童，儿童会出现不对称分布的带状皮损。本文对线状硬皮病的诊断、发病机制及治疗进行了综述。
报告了6例儿童线状硬皮病新病例。他们的年龄在6至17岁之间，其中5例为女孩。一名17岁女孩患有剑伤样硬皮病。采用了多种治疗方式。所有实验室检查均为阴性。
线状硬皮病是一种临床诊断。其发病机制仍然不明。尽管苯妥英和盐酸噻氯匹定应在临床试验中进行评估，但尚未找到始终有效的治疗方法。
