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[使用非甾体类抗炎药后溃疡性直肠结肠炎复发。1例报告并文献复习]

[Reactivation of ulcerative rectocolitis with the use of non-steroidal anti-inflammatory drugs. Report of a case and review of the literature].

作者信息

Dichi I, Dichi J B, Frenhane P, Rodrigues M A, Burini R C, Victória C R

机构信息

Departamento de Clínica Médica, Universidade Estadual Paulista.

出版信息

Arq Gastroenterol. 1995 Oct-Dec;32(4):172-7.

PMID:8734853
Abstract

The case of a patient with ulcerative colitis and isolated sacro-ileitis is presented. She suffered reactivation of the intestinal disease with diclofenac. The patient was allergic to sulfasalazine and was using fish oil fatty acid. The possible mechanisms of reactivation of the inflammatory bowel disease with non-steroidal anti-inflammatory drugs are discussed. It is suggested when necessary the utilization of non-steroidal anti-inflammatory drugs that inhibits the lipoxygenase in these patients.

摘要

本文介绍了一名患有溃疡性结肠炎和孤立性骶髂关节炎的患者病例。她因使用双氯芬酸导致肠道疾病复发。该患者对柳氮磺胺吡啶过敏,正在服用鱼油脂肪酸。文中讨论了非甾体抗炎药导致炎症性肠病复发的可能机制。建议在必要时,这些患者使用抑制脂氧合酶的非甾体抗炎药。

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