结缔组织疾病患者血清对单核细胞红细胞结合及吞噬作用的影响。
The effect of sera from patients with connective tissue diseases on red cell binding and phagocytosis by monocytes.
作者信息
Temple A, Loewi G
出版信息
Immunology. 1977 Jul;33(1):109-14.
Abstract
The uptake by human blood monocytes of sheep erythrocytes treated with rabbit anti-sheep antibody with or without mouse complement was assessed by a radioactive method to discover whether immune complexes would inhibit this reaction. It was found that sera from SLE patients inhibited uptake whereas normal sera enhanced. Some rheumatoid sera and rheumatoid joint fluids inhibited uptake whereas sera from juvenile rheumatoid patients did not.
摘要
采用放射性方法评估人血单核细胞对用兔抗羊抗体处理过的绵羊红细胞的摄取情况，处理过程中添加或不添加小鼠补体，以探究免疫复合物是否会抑制该反应。结果发现，系统性红斑狼疮（SLE）患者的血清会抑制摄取，而正常血清则会增强摄取。一些类风湿患者的血清和类风湿关节液会抑制摄取，而青少年类风湿患者的血清则不会。
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