迟发型超敏反应性皮肤反应部位的增强局部过敏反应。
Augmented local anaphylaxis at sites of delayed hypersensitivity skin reactions.
作者信息
Pearson D J, Taylor G
出版信息
Immunology. 1977 Jul;33(1):115-9.
The magnitude of passive anti-ovalbumin IgE-mediated reactions was quantified at normal skin sites and sites of tuberculin reactions in rats by measurement of induration. It was found that significantly greater immediate reactions occurred at sites of positive tuberculin reactions than at normal skin sites. The augmentation of IgE-mediated reactions was maximal in tuberculin reactions elicited 1 week after active immunization but was still significant in reactions elicited 6 weeks after immunization. The magnitude of the delayed reaction influenced the degree of augmentation of the IgE-mediated reaction observed, greater tuberculin reactions producing greater augmentation. Similar degrees of augmentation by the tuberculin reaction were observed in IgE-mediated reactions elicited 24, 48, and 72 hs after elicitation of the delayed skin test.
通过测量硬结，对大鼠正常皮肤部位和结核菌素反应部位被动抗卵清蛋白IgE介导反应的强度进行了量化。结果发现，结核菌素反应阳性部位出现的即刻反应明显大于正常皮肤部位。IgE介导反应的增强在主动免疫后1周引发的结核菌素反应中最大，但在免疫后6周引发的反应中仍很显著。迟发型反应的强度影响了所观察到的IgE介导反应的增强程度，结核菌素反应越强，增强程度越大。在迟发型皮肤试验激发后24、48和72小时引发的IgE介导反应中，观察到结核菌素反应引起的增强程度相似。
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