IgE介导的反应对大鼠迟发型超敏反应表达的影响。
The influence of IgE-mediated reactions on the expression of delayed hypersensitivity in the rat.
作者信息
Pearson D J, Taylor G
出版信息
Immunology. 1977 Aug;33(2):185-90.
Abstract
The effect of IgE-mediated reactions on the expression of delayed hypersensitivity skin reactions was examined in the rat. It was found that the elicitation of an IgE-mediated reaction at the time of skin test could either potentiate or inhibit the development of delayed reactions. At a fixed level of IgE sensitivity, large delayed reactions were potentiated and small delayed reactions suppressed. These interactions were not dependent on the two types of sensitivity being direct against the same antigen but were dependent on the reaction of IgE with its appropriate antigen.
摘要
在大鼠中研究了IgE介导的反应对迟发型超敏皮肤反应表达的影响。结果发现，在皮肤试验时引发IgE介导的反应可增强或抑制迟发型反应的发展。在固定的IgE敏感性水平下，大的迟发型反应增强，小的迟发型反应受到抑制。这些相互作用并不取决于两种敏感性是否直接针对同一抗原，而是取决于IgE与其相应抗原的反应。
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