Hasin A, Begum R, Khan M R, Ahmed F
Institute of Nutrition and Food Science, University of Dhaka, Bangladesh.
Int J Food Sci Nutr. 1996 May;47(3):273-9. doi: 10.3109/09637489609012588.
A cross-sectional study was carried out to investigate relationship of birth weight with selected biochemical indices of nutritional status of mothers at delivery in poor urban population of Dhaka, Bangladesh. One hundred and fifty one pregnant women of known gestational length, aged 20-30 years, who attended a local maternity hospital for delivery participated in this study. All of them were free from any pregnancy complications or diseases, and delivered a singleton fullterm baby. Socio-economic and obstetric history were taken by interview. Anthropometric data and blood samples were collected on the same day. Twenty per cent of the participants were anaemic (Hb < 11.0 g dl-1), 49% had subnormal (< 4.0 g dl-1) serum albumin and 32.5% had serum vitamin A lower than adequate level (< 30.0 micrograms dl-1). Mothers who gave birth to low birth weight babies had lower levels of haemoglobin (P = 0.06), serum albumin (P = 0.02) and serum vitamin A (P = 0.05) at delivery compared with the mothers who gave birth to normal weight babies. After adjustment for various confounding factors, only serum albumin level remained significantly lower in the mothers of low birth weight babies. Using multiple regression analysis for birth weight, the overall F-ratio was calculated to be 12.5 and was highly significant (P = 0.0000). The adjusted R2 was 0.32. Gestational age, father's occupation, mother's body weight and serum albumin level were found to have significant independent effect on birth weight.
在孟加拉国达卡贫困城市人口中，开展了一项横断面研究，以调查出生体重与分娩时母亲营养状况的选定生化指标之间的关系。151名已知孕周、年龄在20至30岁之间、到当地一家妇产医院分娩的孕妇参与了本研究。她们均无任何妊娠并发症或疾病，并分娩了单胎足月婴儿。通过访谈获取社会经济和产科病史。在同一天收集人体测量数据和血样。20%的参与者贫血（血红蛋白<11.0 g/dl），49%的人血清白蛋白低于正常水平（<4.0 g/dl），32.5%的人血清维生素A低于适当水平（<30.0微克/dl）。与分娩正常体重婴儿的母亲相比，分娩低体重婴儿的母亲在分娩时血红蛋白（P = 0.06）、血清白蛋白（P = 0.02）和血清维生素A（P = 0.05）水平较低。在对各种混杂因素进行调整后，低体重婴儿母亲的血清白蛋白水平仍显著较低。对出生体重进行多元回归分析，计算出的总体F值为12.5，具有高度显著性（P = 0.0000）。调整后的R2为0.32。发现孕周、父亲职业、母亲体重和血清白蛋白水平对出生体重有显著的独立影响。
