L-谷氨酸、L-丙氨酸和L-酪氨酸的随机聚合物在近交系仓鼠中的免疫原性。
Immunogenicity of random polymers of l-glutamic acid, l-alanine and l-tyrosine in inbred hamsters.
作者信息
Luderer A A, Maurer P H, Chack J P
出版信息
Int Arch Allergy Appl Immunol. 1977;54(3):193-7. doi: 10.1159/000231826.
PMID:873620
Abstract
The random terpolymer GAT has been found to be immunogenic in hamsters whereas the random copolymers GA or GT were found to be nonimmunogenic. Although no immune responses to GA or GT could be elicited, the anti-GAT antibody response contained populations inhibited specifically by GA, GT and poly-G. These data suggest that in hamsters, recognition of GAT occurs via determinants which are not present in GA or GT.
摘要
已发现无规三元共聚物GAT在仓鼠中具有免疫原性，而无规共聚物GA或GT则无免疫原性。虽然无法引发对GA或GT的免疫反应，但抗GAT抗体反应包含被GA、GT和聚G特异性抑制的群体。这些数据表明，在仓鼠中，对GAT的识别是通过GA或GT中不存在的决定簇进行的。
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