Novitzky D
University of South Florida, Division of Cardiothoracic Surgery, Tampa 33612, USA.
Curr Opin Cardiol. 1996 Mar;11(2):174-82. doi: 10.1097/00001573-199603000-00011.
The selection of suitable donor hearts is essential for successful recipient outcome. Early allograft failure accounts for approximately 25% of deaths in heart transplantation recipients. The pool of donor organs that become available is inadequate to meet the ever increasing demand. Almost 30% of patients awaiting cardiac transplantation die before a suitable donor heart becomes available. The development of strategies aimed at expanding the donor pool are critically needed. To accomplish this goal it is important to improve donor management, prevent tissue injury following brain death, and attempt to correct donor organ dysfunction.
选择合适的供体心脏对于受体的成功预后至关重要。早期移植物功能衰竭约占心脏移植受体死亡人数的25%。可用的供体器官库不足以满足不断增长的需求。近30%等待心脏移植的患者在获得合适的供体心脏之前死亡。迫切需要制定旨在扩大供体库的策略。为实现这一目标，改善供体管理、预防脑死亡后的组织损伤以及尝试纠正供体器官功能障碍非常重要。
