Costello C
Int Surg. 1977 Apr;62(4):209-12.
A new theory on cause and treatment of peptic diseases proposes that these disorders result from dysfunction of the pyloric muscle causing delay in gastric emptying of solids. It emphasizes the separate function of the duodenal sphincter and the gastric sphincter components of this muscle. Dysfunction of either results in delayed gastric emptying of solids. Peritoneal patch pyloroplasty (PPP) has been devised to correct delayed gastric emptying. Testing of gastric emptying by the barium burger meal is essential to proper diagnosis. One hundred consecutive patients who required surgery for peptic diseases during the past five years have undergone PPP, the first 20 with, and the next 80 without, vagotomy. Results included two deaths and 94 favorable results. Follow-up studies in these patients continue.
一种关于消化性疾病病因及治疗的新理论提出，这些疾病是由幽门肌功能障碍导致固体食物胃排空延迟引起的。该理论强调了十二指肠括约肌和该肌肉的胃括约肌部分的独立功能。其中任何一个功能出现障碍都会导致固体食物胃排空延迟。腹膜贴片幽门成形术（PPP）已被设计用于纠正胃排空延迟。通过钡剂汉堡餐测试胃排空对于正确诊断至关重要。在过去五年中，连续100例因消化性疾病需要手术的患者接受了PPP，前20例同时进行了迷走神经切断术，后80例未进行。结果包括2例死亡和94例良好结果。对这些患者的随访研究仍在继续。
