Schrell U M, Nomikos P, Schrauzer T, Anders M, Marschalek R, Adams E F, Fahlbusch R
Department of Neurosurgery, University of Erlangen-Nürnberg, Federal Republic of Germany.
Acta Neurochir Suppl. 1996;65:54-7. doi: 10.1007/978-3-7091-9450-8_16.
Though meningiomas are benign intracranial tumors, a minor group invades the skull base and the connective tissue of the sinus cavernous inducing neurological deficits. These patients can not be cured by surgical treatment. Therefore, the development of an adjuvant medical therapy has been the goal during the last decade. We report here on different medical concepts which are based on steroids, amines, growth factor antagonists and cytokines. In addition, our data give evidence that the growth of intracranial meningiomas is under multifactorial proliferative control.
虽然脑膜瘤是良性颅内肿瘤，但一小部分会侵犯颅底和海绵窦的结缔组织，导致神经功能缺损。这些患者无法通过手术治愈。因此，在过去十年中，开发辅助药物治疗一直是目标。我们在此报告基于类固醇、胺类、生长因子拮抗剂和细胞因子的不同医学概念。此外，我们的数据表明颅内脑膜瘤的生长受多因素增殖控制。
