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The expression of alpha 6 and beta 4 integrin genes are differentially regulated by all-trans-retinoic acid (RA) in cultured human keratinocytes.

作者信息

Laurikainen L, Carey T, Peltonen J

机构信息

Department of Dermatology, University of Turku, Finland.

出版信息

Arch Dermatol Res. 1996 May;288(5-6):270-3. doi: 10.1007/BF02530100.

DOI:10.1007/BF02530100
PMID:8738575
Abstract
摘要

相似文献

1
The expression of alpha 6 and beta 4 integrin genes are differentially regulated by all-trans-retinoic acid (RA) in cultured human keratinocytes.
Arch Dermatol Res. 1996 May;288(5-6):270-3. doi: 10.1007/BF02530100.
2
Effects of retinoic acid on interleukin-1 alpha and -1 beta expression by normal human keratinocytes cultured in defined medium.
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4
Expression of the alpha 6A integrin splice variant in developing mouse embryonic stem cell aggregates and correlation with cardiac muscle differentiation.α6A整合素剪接变体在发育中的小鼠胚胎干细胞聚集体中的表达及其与心肌分化的相关性。
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5
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6
Epidermal growth factor-, transforming growth factor-beta-, retinoic acid- and 1,25-dihydroxyvitamin D3-regulated expression of the novel protein PTPIP51 in keratinocytes.
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7
Regulation of expression and phosphorylation of A9/alpha 6 beta 4 integrin in normal and neoplastic keratinocytes.
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8
Suprabasal expression of epidermal alpha 2 beta 1 and alpha 3 beta 1 integrins in skin treated with topical retinoic acid.局部外用维甲酸治疗的皮肤中表皮α2β1和α3β1整合素的基底层上表达
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9
The CYP26 inhibitor R115866 potentiates the effects of all-trans retinoic acid on cultured human epidermal keratinocytes.细胞色素P450 26（CYP26）抑制剂R115866可增强全反式维甲酸对培养的人表皮角质形成细胞的作用。
Br J Dermatol. 2009 Mar;160(3):505-13. doi: 10.1111/j.1365-2133.2008.08960.x. Epub 2008 Dec 11.
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Differential gene induction of human beta-defensins (hBD-1, -2, -3, and -4) in keratinocytes is inhibited by retinoic acid.维甲酸可抑制角质形成细胞中人类β-防御素（hBD-1、-2、-3和-4）的差异基因诱导。
J Invest Dermatol. 2004 Sep;123(3):522-9. doi: 10.1111/j.0022-202X.2004.23234.x.

本文引用的文献

1
Hyperglycemic glucose concentrations up-regulate the expression of type VI collagen in vitro. Relevance to alterations of peripheral nerves in diabetes mellitus.高血糖浓度在体外上调VI型胶原蛋白的表达。与糖尿病外周神经改变的相关性。
Am J Pathol. 1993 May;142(5):1586-97.
2
The alpha 6 beta 4 integrin is a receptor for both laminin and kalinin.α6β4整合素是层粘连蛋白和kalinin的受体。
Exp Cell Res. 1994 Apr;211(2):360-7. doi: 10.1006/excr.1994.1099.
3
Altered expression in squamous carcinoma cells of an orientation restricted epithelial antigen detected by monoclonal antibody A9.
单克隆抗体A9检测到的一种定向受限上皮抗原在鳞状癌细胞中的表达改变。
Cancer Res. 1986 Jul;46(7):3614-23.
4
A complex of platelet glycoproteins Ic and IIa identified by a rat monoclonal antibody.一种由大鼠单克隆抗体识别的血小板糖蛋白Ic和IIa复合物。
J Biol Chem. 1987 Jul 25;262(21):10376-83.
5
Northern blot normalization with a 28S rRNA oligonucleotide probe.使用28S rRNA寡核苷酸探针进行Northern印迹标准化。
Nucleic Acids Res. 1989 Sep 12;17(17):7115. doi: 10.1093/nar/17.17.7115.
6
All-trans retinoic acid stimulates growth of adult human keratinocytes cultured in growth factor-deficient medium, inhibits production of thrombospondin and fibronectin, and reduces adhesion.全反式维甲酸可刺激在缺乏生长因子的培养基中培养的成人角质形成细胞生长，抑制血小板反应蛋白和纤连蛋白的产生，并降低黏附性。
J Invest Dermatol. 1989 Oct;93(4):449-54. doi: 10.1111/1523-1747.ep12284020.
7
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.采用酸性硫氰酸胍-苯酚-氯仿萃取法一步分离RNA的方法。
Anal Biochem. 1987 Apr;162(1):156-9. doi: 10.1006/abio.1987.9999.
8
Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes.α6β4整合素异二聚体是半桥粒的一个组成部分。
Proc Natl Acad Sci U S A. 1990 Nov;87(22):8970-4. doi: 10.1073/pnas.87.22.8970.
9
Molecular cloning of the human alpha 6 integrin subunit. Alternative splicing of alpha 6 mRNA and chromosomal localization of the alpha 6 and beta 4 genes.人α6整合素亚基的分子克隆。α6 mRNA的可变剪接以及α6和β4基因的染色体定位。
Eur J Biochem. 1991 Jul 15;199(2):425-33. doi: 10.1111/j.1432-1033.1991.tb16140.x.
10
Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.整合素α6/β4复合物位于半桥粒中，提示其在表皮细胞与基底膜黏附中起主要作用。
J Cell Biol. 1991 May;113(4):907-17. doi: 10.1083/jcb.113.4.907.