Kocijancic S, Drevensek G, Budihna M V
Department of Physics and Technical Craft, Faculty of Education, University of Ljubljana, Slovenia.
Pflugers Arch. 1996;431(6 Suppl 2):R273-4. doi: 10.1007/BF02346374.
The left ventricular pressure (LVP) and ECG signals that appear during and after ischaemia tend to be very irregular (fibrillation, arrhythmia). Computer based data acquisition system, that we developed to support experiments on isolated Langendorff's rat heart, enabled the usage of methods derived from non-linear dynamics. To classify the irregularity of heart action, ECG and LVP time series have been used to calculate correlation dimension (D2) and largest Lyapunov exponent. We compared the results of signals derived from isolated heart at standard conditions and hearts rendered ischaemic for 60 minutes. Our results show that the level of irregularity can be classified efficiently using the quoted approach.
缺血期间及之后出现的左心室压力(LVP)和心电图信号往往非常不规则(颤动、心律失常)。我们开发的基于计算机的数据采集系统用于支持对离体朗格多夫大鼠心脏的实验,该系统使得源自非线性动力学的方法得以应用。为了对心脏活动的不规则性进行分类,已使用心电图和左心室压力时间序列来计算关联维数(D2)和最大Lyapunov指数。我们比较了在标准条件下离体心脏以及缺血60分钟的心脏所产生信号的结果。我们的结果表明,使用上述方法可以有效地对不规则程度进行分类。