Lauria G, Gentile M, Fassetta G, Casetta I, Agnoli F, Andreotta G, Barp C, Caneve G, Cavallaro A, Cielo R
Section of Neuroepidemiology, University of Ferrara, Italy.
Stroke. 1995 Oct;26(10):1787-93. doi: 10.1161/01.str.26.10.1787.
We sought to register the incidence rate, risk factors, and case-fatality rate of all the new cases of first-ever-in-a-lifetime stroke in the province of Beluno, Italy. This study aimed to provide an epidemiological survey of cerebrovascular disease that could supply investigative objectives and support information for regional healthcare facilities planning.
We undertook a prospective population-based study in the territory of the 1st, 2nd, 3rd, and 4th local health units in the province of Belluno, an area located in northeast Italy (population, 211 389).
In the first year of the study (June 1, 1992, to May 31, 1993), 474 cases of first-ever stroke were registered. The crude annual incidence rate was 2.24/1000 (2.01/1000 for men and 2.45/1000 for women). After adjustment to the European population, the incidence rate for first stroke was 1.70/1000 per year. The pathological diagnosis was confirmed by a CT scan in 89.5% of cases. Cerebral infarction accounted for 319 cases, while 93 patients suffered a primary intracerebral hemorrhage, 12 patients a subarachnoid hemorrhage, and 50 patients a stroke of unknown origin. The overall 30-day case-fatality rate was 33%, and the mortality within the first week from stroke onset was 23%. The recurrence rate after 1 month was 1.9%. After 1 month, 46% of our patients were functionally independent in activities of daily living.
Our first-year results confirm the fairly high risk for stroke in central and northern Italy and support European findings regarding risk factors for stroke.
我们试图记录意大利贝卢诺省所有首次发生的终生性卒中的新发病例的发病率、危险因素及病死率。本研究旨在提供一项脑血管疾病的流行病学调查，可为区域医疗设施规划提供调查目标及支持信息。
我们在意大利东北部贝卢诺省第1、2、3和4个地方卫生单位辖区内开展了一项基于人群的前瞻性研究（人口数为211389）。
在研究的第一年（1992年6月1日至1993年5月31日），共记录了474例首次卒中病例。粗年发病率为2.24/1000（男性为2.01/1000，女性为2.45/1000）。经欧洲人口调整后，首次卒中的发病率为每年1.70/1000。89.5%的病例经CT扫描确诊病理诊断。脑梗死319例，原发性脑出血93例，蛛网膜下腔出血12例，不明原因卒中50例。30天总病死率为33%，卒中发病后第一周内的死亡率为23%。1个月后的复发率为1.9%。1个月后，46%的患者在日常生活活动中功能独立。
我们第一年的研究结果证实了意大利中部和北部卒中风险相当高，并支持了欧洲关于卒中危险因素的研究结果。
