De Vito E L, Quadrelli S A, Montiel G C, Roncoroni A J
Instituto de Investigaciones Médicas Alfredo Lanari, Universidad de Buenos Aires, Argentina.
Respiration. 1996;63(3):187-90. doi: 10.1159/000196542.
A 35-year-old man presented bilateral phrenic paralysis 7 months after radio-therapy for treatment of Hodgkin's lymphoma. Diaphragmatic dysfunction appeared after complete lymphoma remission and 4 months after chemotherapy discontinuation. There were no other potential causes. Idiopathic diaphragmatic paralysis was unlikely because it is usually unilateral. Radiation-induced neuropathy is well documented in other nerves as the brachial plexus. The timing, the applied dose and the location of the nerve within the radiation field are suggestive of radiation-induced phrenic nerve damage. Partial recovery was achieved after 4 years' follow-up.
一名35岁男性在接受放射治疗霍奇金淋巴瘤7个月后出现双侧膈神经麻痹。膈肌功能障碍出现在淋巴瘤完全缓解后以及化疗停止4个月后。不存在其他潜在病因。特发性膈肌麻痹不太可能，因为其通常为单侧性。放射诱发的神经病变在其他神经如臂丛神经中已有充分记录。神经在放射野内的时间、所应用的剂量以及位置提示为放射诱发的膈神经损伤。经过4年随访实现了部分恢复。
