Chen Hsuan-Yu, Chen Hung-Chen, Lin Meng-Chih, Liaw Mei-Yun
From the Department of Physical Medicine and Rehabilitation (H-YC), Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine (M-YL), Department of Physical Medicine and Rehabilitation, Chang Gung University College of Medicine; and Division of Pulmonary and Critical Care Medicine (H-CC, M-CL), Chang Gung Memorial Hospital-Kaohsiung Medical Center, Department of Internal Medicine, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Medicine (Baltimore). 2015 Aug;94(31):e1288. doi: 10.1097/MD.0000000000001288.
Bilateral diaphragmatic paralysis (BDP) manifests as respiratory muscle weakness, and its association with critical illness polyneuropathy (CIP) was rarely reported. Here, we present a patient with BDP related to CIP, who successfully avoided tracheostomy after diagnosis and management.A 71-year-old male presented with acute respiratory failure after sepsis adequately treated. Repeated intubation occurred because of carbon dioxide retention after each extubation. After eliminating possible factors, septic shock-induced respiratory muscle weakness was suspected. Physical examination, a nerve conduction study, and chest ultrasound confirmed our impression.Pulmonary rehabilitation and reconditioning exercises were arranged, and the patient was discharged with a diagnosis of BDP.The diagnosis of BDP is usually delayed, and there are only sporadic reports on its association with polyneuropathy, especially in patients with preserved limb muscle function. Therefore, when physicians encounter patients that are difficult to wean from mechanical ventilation, CIP associated with BDP should be considered in the differential diagnosis.
双侧膈肌麻痹(BDP)表现为呼吸肌无力,其与危重病性多发性神经病(CIP)的关联鲜有报道。在此,我们报告一例与CIP相关的BDP患者,该患者在诊断和治疗后成功避免了气管切开术。一名71岁男性在脓毒症得到充分治疗后出现急性呼吸衰竭。每次拔管后均因二氧化碳潴留而反复插管。在排除可能因素后,怀疑是脓毒性休克引起的呼吸肌无力。体格检查、神经传导研究和胸部超声证实了我们的判断。安排了肺康复和适应性锻炼,患者出院时诊断为BDP。BDP的诊断通常会延迟,关于其与多发性神经病关联的报道也仅为零星个案,尤其是在肢体肌肉功能保留的患者中。因此,当医生遇到难以脱离机械通气的患者时,鉴别诊断中应考虑与BDP相关的CIP。