Calvo A, Pastor L M, Gallego-Huidobro J, Horn R, Pallares J
Department of Cellular Biology, Medical School, University of Murcia, Spain.
Acta Anat (Basel). 1995;154(3):186-95. doi: 10.1159/000147768.
The morphology of the spermatozoa in the cauda epididymidis of 6- and 24-month-old (adult and aged) hamster was studied by electron microscopy. Lesions found in the spermatozoa included alterations in the acrosomal matrix and nuclear membranes, abnormal or absent mitochondria, alterations in the axonemes, dense fibres and microtubules, and bent flagella. All these abnormalities are similar to those found in other species and few alterations were exclusive to the older animals. Ultrastructurally abnormal spermatozoa were observed in both groups but were present at a significantly greater frequency in aged hamsters (p < 0.005). the percentage of sperm with abnormal acrosomes, mitochondria and dense fibres and of bent (but not disrupted) spermatozoa was significantly greater in the older animals. These results show that the ultrastructural alterations in hamster sperm are similar to those found in other mammals. Moreover, the percentage of ultrastructurally abnormal spermatozoa in aged hamsters is greater than 6-month-old hamsters, this increase is not accompanied by any new kinds of alteration.
通过电子显微镜研究了6个月和24个月大（成年和老年）仓鼠附睾尾部精子的形态。精子中发现的病变包括顶体基质和核膜的改变、线粒体异常或缺失、轴丝、致密纤维和微管的改变以及鞭毛弯曲。所有这些异常与其他物种中发现的异常相似，很少有改变是老年动物特有的。两组均观察到超微结构异常的精子，但老年仓鼠中此类精子的出现频率显著更高（p < 0.005）。老年动物中顶体、线粒体和致密纤维异常以及鞭毛弯曲（但未断裂）的精子百分比显著更高。这些结果表明，仓鼠精子的超微结构改变与其他哺乳动物相似。此外，老年仓鼠中超微结构异常精子的百分比高于6个月大的仓鼠，这种增加并未伴随任何新类型的改变。
