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酿酒酵母第十四条染色体上一段17,933碱基对的序列包含RHO2、TOP2、MKT1和END3基因以及五个新的开放阅读框。

The sequence of a 17,933 bp segment of Saccharomyces cerevisiae chromosome XIV contains the RHO2, TOP2, MKT1 and END3 genes and five new open reading frames.

作者信息

Soler-Mira A, Saiz J E, Ballesta J P, Remacha M

机构信息

Centro de Biología Molecular Severo Ochoa, CSIC and UAM, Cantoblanco, Madrid, Spain.

出版信息

Yeast. 1996 Apr;12(5):485-91. doi: 10.1002/(sici)1097-0061(199604)12:5<485::aid-yea928>3.0.co;2-u.

Abstract

We report the DNA sequence of a 17,933 bp fragment from the left arm of chromosome XIV of Saccharomyces cerevisiae. Analysis of the sequence reveals the presence of ten open reading frames (ORFs) larger than 100 codons. Four of these were previously identified as genes RHO2, TOP2, MKT1 and END3. Additionally, the NH2 end coding region of PMS1 is found in the 3' end of the sequence. No significant homology to any known protein has been found for the other five ORFs.

摘要

我们报道了来自酿酒酵母第十四号染色体左臂的一个17933 bp片段的DNA序列。对该序列的分析揭示了存在十个大于100个密码子的开放阅读框(ORF)。其中四个先前已被鉴定为RHO2、TOP2、MKT1和END3基因。此外,PMS1的NH2末端编码区位于该序列的3'末端。其他五个ORF未发现与任何已知蛋白质有显著同源性。

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