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对酿酒酵母11号染色体上位于FAS1和LAP基因座之间的一个36.2 kb片段进行DNA测序。

DNA sequencing of a 36.2 kb fragment located between the FAS1 and LAP loci of chromosome XI of Saccharomyces cerevisiae.

作者信息

Vandenbol M, Bolle P A, Dion C, Portetelle D, Hilger F

机构信息

Unité de Microbiologie, Faculté des Sciences Agronomiques de Gembloux, Belgium.

出版信息

Yeast. 1994 Apr;10 Suppl A:S35-40. doi: 10.1002/yea.320100005.

DOI:10.1002/yea.320100005
PMID:8091859
Abstract

We have completely sequenced on both strands a continuous DNA segment of 36.2 kb located on the left arm of Saccharomyces cerevisiae chromosome XI. Sequence analysis reveals the presence of 20 open reading frames (ORFs) at least 100 amino acids long. Five of these ORFs correspond to known genes; five others show homology with known proteins; the ten remaining ORFs identified show no detectable homology with other protein sequences contained in data banks and may represent new biological functions.

摘要

我们对位于酿酒酵母第十一染色体左臂上一段36.2 kb的连续DNA片段进行了双链完全测序。序列分析显示存在20个开放阅读框（ORF），其长度至少为100个氨基酸。其中5个ORF对应已知基因；另外5个与已知蛋白质具有同源性；其余10个鉴定出的ORF与数据库中包含的其他蛋白质序列无明显同源性，可能代表新的生物学功能。

相似文献

1
DNA sequencing of a 36.2 kb fragment located between the FAS1 and LAP loci of chromosome XI of Saccharomyces cerevisiae.对酿酒酵母11号染色体上位于FAS1和LAP基因座之间的一个36.2 kb片段进行DNA测序。
Yeast. 1994 Apr;10 Suppl A:S35-40. doi: 10.1002/yea.320100005.
2
Sequencing and analysis of a 20.5 kb DNA segment located on the left arm of yeast chromosome XI.对位于酵母第十一染色体左臂上的一段20.5千碱基对DNA片段进行测序和分析。
Yeast. 1994 Apr;10 Suppl A:S25-33. doi: 10.1002/yea.320100004.
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The complete sequence of a 33 kb fragment on the right arm of chromosome II from Saccharomyces cerevisiae reveals 16 open reading frames, including ten new open reading frames, five previously identified genes and a homologue of the SCO1 gene.来自酿酒酵母二号染色体右臂上一个33 kb片段的完整序列揭示了16个开放阅读框，其中包括10个新的开放阅读框、5个先前已鉴定的基因以及SCO1基因的一个同源物。
Yeast. 1994 Apr;10 Suppl A:S75-80. doi: 10.1002/yea.320100010.
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Sequence analysis of a 3.5 Kb EcoRI fragment from the left arm of Saccharomyces cerevisiae chromosome XI reveals the location of the MBR1 gene and a sequence related to a GTPase-activating protein.对酿酒酵母第十一染色体左臂上一个3.5千碱基对的EcoRI片段进行序列分析，揭示了MBR1基因的位置以及一个与GTP酶激活蛋白相关的序列。
Yeast. 1994 Feb;10(2):257-64. doi: 10.1002/yea.320100212.
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Sequencing of a 40.5 kb fragment located on the left arm of chromosome VII from Saccharomyces cerevisiae.对酿酒酵母七号染色体左臂上一个40.5 kb片段进行测序。
Yeast. 1997 Jan;13(1):55-64. doi: 10.1002/(SICI)1097-0061(199701)13:1<55::AID-YEA48>3.0.CO;2-9.
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Sequencing and analysis of 51.6 kilobases on the left arm of chromosome XI from Saccharomyces cerevisiae reveals 23 open reading frames including the FAS1 gene.对酿酒酵母XI号染色体左臂上51.6千碱基的序列进行测序和分析，发现了23个开放阅读框，其中包括FAS1基因。
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The sequence of a 12 kb fragment on the left arm of yeast chromosome XI reveals five new open reading frames, including a zinc finger protein and a homolog of the UDP-glucose pyrophosphorylase from potato.
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The sequence of a 8 kb segment on the right arm of yeast chromosome VII identifies four new open reading frames and the genes for yTAFII145.酵母染色体VII右臂上一个8千碱基片段的序列鉴定出四个新的开放阅读框以及yTAFII145的基因。
Yeast. 1997 Mar 30;13(4):365-8. doi: 10.1002/(SICI)1097-0061(19970330)13:4<365::AID-YEA78>3.0.CO;2-F.
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Sequencing analysis of a 36.8 kb fragment of yeast chromosome XV reveals 26 open reading frames including SEC63, CDC31, SUG2, GCD1, RBL2, PNT1, PAC1 and VPH1.对酵母第十五号染色体上一个36.8 kb片段的测序分析揭示了26个开放阅读框，包括SEC63、CDC31、SUG2、GCD1、RBL2、PNT1、PAC1和VPH1。
Yeast. 1997 Apr;13(5):483-7. doi: 10.1002/(SICI)1097-0061(199704)13:5<483::AID-YEA105>3.0.CO;2-U.
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The sequence of a 9.3 kb segment located on the left arm of the yeast chromosome XI reveals five open reading frames including the CCE1 gene and putative products related to MYO2 and to the ribosomal protein L10.位于酵母第十一染色体左臂上一个9.3 kb片段的序列揭示了五个开放阅读框，包括CCE1基因以及与MYO2和核糖体蛋白L10相关的推定产物。
Yeast. 1992 Nov;8(11):987-95. doi: 10.1002/yea.320081109.

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Molecular cloning and expression of the Candida albicans TOP2 gene allows study of fungal DNA topoisomerase II inhibitors in yeast.白色念珠菌TOP2基因的分子克隆与表达使得在酵母中研究真菌DNA拓扑异构酶II抑制剂成为可能。
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Characterization of a serum response factor-like protein in Saccharomyces cerevisiae, Rlm1, which has transcriptional activity regulated by the Mpk1 (Slt2) mitogen-activated protein kinase pathway.
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Mol Cell Biol. 1997 May;17(5):2615-23. doi: 10.1128/MCB.17.5.2615.