Imai K, Chinzei M, Oguchi K, Tamai H, Sato Y, Umeyama T, Tagami M, Hanaoka K
Department of Anesthesiology, Branch Hospital, University of Tokyo.
Masui. 1996 Jul;45(7):837-41.
We investigated the usefulness of nasal/oral discriminate sampling system (NODSS) that had been developed recently in order to obtain the accurate end-tidal carbon dioxide (PET(CO2)) from a spontaneously breathing patient through a nomal airway. Fifty patients were monitored using a capnograph with NODSS following extubation in the postanesthesia unit. PET(CO2) data were collected by means of nasal, oral or nasal/oral sampling. The levels of arterial carbon dioxide (PaCO2) were determined simultaneously. In addition to examining the correlation between PET(CO2) and PaCO2, we investigated the influence of method of anesthesia, age and respiratory rate on the (PaCO2 - PET(CO2)) gradient. In most patients without nasal obstruction breathing through the nostril, PET(CO2) determined by selective nasal sampling was closer to PaCO2 than those by oral or nasal/oral sampling. Furthermore, the mean (PaCO2 - PET(CO2)) gradient was 4.98 mmHg in patients aged over 60, while it was 2.02 mmHg in patients aged under 60, suggesting that PET(CO2) could not be a good index in elderly people. There was no significant difference in the mean (PaCO2 - PET(CO2)) gradient among different methods of anesthesia. In conclusion, NODSS was useful in determining PET(CO2) more accurately and estimating PaCO2 precisely when used in relatively young people by selective nasal or oral sampling.
我们研究了最近开发的鼻/口鉴别采样系统(NODSS)的实用性,该系统旨在通过正常气道从自主呼吸的患者中获取准确的呼气末二氧化碳(PET(CO2))。在麻醉后监护病房,对50例患者拔管后使用带有NODSS的二氧化碳监测仪进行监测。通过鼻、口或鼻/口采样收集PET(CO2)数据。同时测定动脉二氧化碳(PaCO2)水平。除了检查PET(CO2)与PaCO2之间的相关性外,我们还研究了麻醉方法、年龄和呼吸频率对(PaCO2 - PET(CO2))梯度的影响。在大多数无鼻塞且通过鼻孔呼吸的患者中,通过选择性鼻采样测定的PET(CO2)比通过口或鼻/口采样测定的更接近PaCO2。此外,60岁以上患者的平均(PaCO2 - PET(CO2))梯度为4.98 mmHg,而60岁以下患者为2.02 mmHg,这表明PET(CO2)在老年人中可能不是一个好的指标。不同麻醉方法之间的平均(PaCO2 - PET(CO2))梯度无显著差异。总之,NODSS在相对年轻的人群中通过选择性鼻或口采样更准确地测定PET(CO2)并精确估计PaCO2方面是有用的。