Takeda Y, Gon S, Takei H, Sendo F
Department of Immunology and Parasitology, Yamagata University School of Medicine.
Nihon Rinsho. 1996 Jul;54(7):1888-94.
Intracellular signal transduction pathways induced by in the reaction of TNF and TNF receptors has been clarified through finding of various TNF receptor associated intracytoplasmic molecules. The possible role of these signal transduction pathways for apoptosis induced by TNF is discussed.
通过发现各种与肿瘤坏死因子(TNF)受体相关的胞浆内分子,TNF与TNF受体反应所诱导的细胞内信号转导途径已得到阐明。本文讨论了这些信号转导途径在TNF诱导的细胞凋亡中可能发挥的作用。