Owunwanne A, Church L B, Blau M
J Nucl Med. 1977 Aug;18(8):822-6.
The effect of oxygen on the reduction of sodium pertechnetate by stannous chloride has been investigated using a paper electrophoresis method. It has been shown that oxygen interferes with the reduction process by oxidizing stannous ion, Sn(II), to stannic, Sn(IV), thereby leaving less Sn(II) available for the reduction of pertechnetate ion. In a solution of 1.66 X 13(-3)M TcO4- saturated with oxygen, a 3.4 molar ratio of Sn(II) to TcO4- was required for complete reduction of TcO4-, whereas in a nitrogen atmosphere, a 2.4 molar ratio was required for the same purpose. The oxygen interference increases as the concentration of TcO4- decreases. In a nitrogen atmosphere, 1.40 and 10.05 molar ratios of Sn(II) to TcO4- were required for the complete reduction of 1.66 X 10(-2)M and 1.66 X 10(-5)M TcO4- respectively. Once the reduction is accomplished, however, it is not easily reversible. Bubbling with oxygen for 1 hr had no effect on the quantity of reduced technetium.
采用纸电泳法研究了氧气对氯化亚锡还原高锝酸钠的影响。结果表明，氧气通过将亚锡离子（Sn(II)）氧化为锡离子（Sn(IV)）来干扰还原过程，从而使可用于还原高锝酸根离子的Sn(II)减少。在氧气饱和的1.66×10⁻³M TcO₄⁻溶液中，完全还原TcO₄⁻需要Sn(II)与TcO₄⁻的摩尔比为3.4，而在氮气气氛中，达到相同目的需要的摩尔比为2.4。随着TcO₄⁻浓度的降低，氧气的干扰作用增强。在氮气气氛中，完全还原1.66×10⁻²M和1.66×10⁻⁵M TcO₄⁻分别需要Sn(II)与TcO₄⁻的摩尔比为1.40和10.05。然而，一旦还原完成，就不容易逆转。用氧气鼓泡1小时对还原后的锝的量没有影响。
