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荷兰所有年龄组的糖尿病发病率都在上升吗?荷兰哨兵实践网络第二项研究的结果。

Is the incidence of diabetes increasing in all age-groups in The Netherlands? Results of the second study in the Dutch Sentinel Practice Network.

作者信息

Ruwaard D, Gijsen R, Bartelds A I, Hirasing R A, Verkleij H, Kromhout D

机构信息

National Institute of Public Health and Environmental Protection, Netherlands.

出版信息

Diabetes Care. 1996 Mar;19(3):214-8. doi: 10.2337/diacare.19.3.214.

DOI:10.2337/diacare.19.3.214
PMID:8742564
Abstract

OBJECTIVE

To assess possible changes in the incidence of diabetes in all age-groups in The Netherlands during a 10-year period (1980-1983/1990-1992).

RESEARCH DESIGN AND METHODS

Since 1970, a network of sentinel stations (the Dutch Sentinel Practice Network) consisting of approximately 1% of the Dutch population has been in operation to gain insight into the morbidity patterns of the Dutch population as recorded by general practitioners. One of the items recorded from 1990 to 1992 was the incidence of diabetes. The first study with a similar design that registered the incidence of diabetes was conducted from 1980 to 1983.

RESULTS

The overall incidence of diabetes increased significantly by 12.1% in the period between the two studies. This overall increase can largely be attributed to a statistically significant increase in the age-group 45-64 years (30.5%). Although not statistically significant, the 36% increase of diabetes in the age-group 0-19 years is in accordance with the increase of type I diabetes based on the first and second nationwide retrospective studies covering the total Dutch population.

CONCLUSIONS

There is a marked increase in the incidence of diabetes in the age-group 45-64 years. This selective increase is probably not due to a real rise caused by changes in exposure to risk factors but to an earlier recognition of symptoms and signs of diabetes followed by blood glucose measurements and/or to more intensive case finding in general practice.

摘要

目的

评估荷兰所有年龄组在10年期间(1980 - 1983年/1990 - 1992年)糖尿病发病率的可能变化。

研究设计与方法

自1970年以来,一个由约1%荷兰人口组成的哨点站网络(荷兰哨点实践网络)一直在运行,以深入了解全科医生记录的荷兰人群发病模式。1990年至1992年记录的项目之一是糖尿病发病率。第一项采用类似设计记录糖尿病发病率的研究是在1980年至1983年进行的。

结果

在两项研究期间,糖尿病的总体发病率显著增加了12.1%。这种总体增加在很大程度上可归因于45 - 64岁年龄组的统计学显著增加(30.5%)。虽然无统计学意义,但0 - 19岁年龄组糖尿病发病率36%的增加与基于覆盖荷兰全体人口的第一次和第二次全国性回顾性研究的1型糖尿病增加情况一致。

结论

45 - 64岁年龄组的糖尿病发病率显著增加。这种选择性增加可能不是由于危险因素暴露变化导致的实际上升,而是由于对糖尿病症状和体征的更早认识,随后进行血糖测量和/或在全科医疗中更积极的病例发现。

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