van Doorn A, Bovendeerd P H, Nicolay K, Drost M R, Janssen J D
Department of Mechanical Engineering, Eindhoven University of Technology, The Netherlands.
Eur J Morphol. 1996;34(1):5-10. doi: 10.1076/ejom.34.1.5.13156.
Biomechanical studies have shown that the distribution of stress and strain in biological tissue is strongly dependent on fibre orientation. Therefore, to analyze the local mechanical load, accurate data on muscle fibre orientation are needed. Traditional techniques to determine fibre orientation are inherently invasive. Here we used Diffusion Weighted MRI to non-invasively determine, in each image voxel of 0.23 x 0.23 mm, the diffusion tensor of water in the cat semimembranosus muscle. The direction corresponding to the largest eigenvector of this tensor was calculated. This direction was found to correspond qualitatively to the muscular fibre direction, as determined by visual inspection.
生物力学研究表明，生物组织中应力和应变的分布强烈依赖于纤维方向。因此，为了分析局部机械负荷，需要有关肌肉纤维方向的准确数据。传统的确定纤维方向的技术本质上具有侵入性。在这里，我们使用扩散加权磁共振成像以非侵入性方式在猫半膜肌的每个0.23×0.23毫米的图像体素中确定水的扩散张量。计算出对应于该张量最大特征向量的方向。发现该方向在质量上与通过目视检查确定的肌肉纤维方向相对应。
