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[脓毒症的发病机制及采用非药物方法进行治疗的可能性]

[The pathogenesis of sepsis and the possibilities for its treatment using nondrug methods].

作者信息

Kariakin A M, Kucher V V

出版信息

Vestn Khir Im I I Grek. 1995;154(3):9-12.

PMID:8743775
Abstract

The substantiation of views to the foci of the "cryptogenic" infection and its nature in sepsis is given. The state of the redox system, immunological status and functions of the liver and kidneys in patients with complicated sepsis are investigated. The data on the influence of nonmedicamental methods (hemodialysis, AUVIB, HBO, EHS) upon the parameters of the redox system, cellular and humoral immunity in acute sepsis patients are presented. A complex of nonmedicamental methods, most effective in correction of homeostasis disturbances in sepsis is suggested and tested. An analysis of efficiency of each of the nonmedicamental methods has shown that they statistically promote the decreasing of lethality indices and the duration of the hospital treatment.

摘要

给出了关于脓毒症中“隐源性”感染病灶及其性质的观点依据。对复杂脓毒症患者的氧化还原系统状态、免疫状态以及肝脏和肾脏功能进行了研究。展示了非药物方法(血液透析、AUVIB、高压氧治疗、体外血液刺激)对急性脓毒症患者氧化还原系统参数、细胞免疫和体液免疫的影响数据。提出并测试了一组在纠正脓毒症中稳态紊乱方面最有效的非药物方法。对每种非药物方法的有效性分析表明,它们在统计学上有助于降低致死率指标和缩短住院治疗时间。

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