Gratwohl A
Department of Internal Medicine and Research, Kantonsspital, Basel, Switzerland.
Arch Immunol Ther Exp (Warsz). 1995;43(2):77-81.
The European Group of Blood and Marrow Transplantation (EBMT) is collecting information on incidence of bone marrow transplantation in Europe. 203 teams in 26 European countries performed in 1992 a total of 6065 bone marrow transplants (BMT). There were 2666 (44%) allogeneic transplants from 2171 HLA identical sibling donors, 170 non-identical family donors, 29 twin donors and 296 unrelated volunteer donors. There were 3399 autologous transplants (56%): 2494 autologous BMT, 644 autologous peripheral blood stem cell transplants and 261 combined autologous bone marrow peripheral blood stem cell transplants. Transplant indications were leukemias in 2963 patients (49%) (1987 allogeneic, 976 autologous), lymphoproliferative disorders in 1890 patients (31%) (201 allogeneic, 1689 autologous), solid tumors in 739 patients (12%) (10 allogeneic, 739 autologous), aplastic anemia in 194 patients (3%) (193 allogeneic, 1 autologous), thalassemia in 128 patients (2%) (all allogeneic), inborn errors in 115 patients (2%) (all allogeneic) and miscellaneous disorders in 36 patients (32 allogeneic, 4 autologous). Main differences were observed in the number of transplanting teams, and in the number of allogeneic and autologous transplants performed in the different European countries compared to the number of inhabitants.
欧洲血液和骨髓移植组（EBMT）正在收集欧洲骨髓移植发病率的信息。1992年，欧洲26个国家的203个团队共进行了6065例骨髓移植（BMT）。其中有2666例（44%）为同种异体移植，供者包括2171例HLA配型相同的同胞、170例配型不同的家庭成员、29例双胞胎以及296例无关志愿供者。有3399例自体移植（56%）：2494例自体BMT、644例自体外周血干细胞移植以及261例自体骨髓与外周血干细胞联合移植。移植适应证为白血病的患者有2963例（49%）（1987例同种异体移植，976例自体移植），淋巴增生性疾病患者1890例（31%）（201例同种异体移植，1689例自体移植），实体瘤患者739例（12%）（10例同种异体移植，739例自体移植），再生障碍性贫血患者194例（3%）（193例同种异体移植，1例自体移植），地中海贫血患者128例（2%）（均为同种异体移植），先天性疾病患者115例（2%）（均为同种异体移植），其他杂症患者36例（32例同种异体移植，4例自体移植）。与居民数量相比，不同欧洲国家在移植团队数量以及同种异体和自体移植数量上存在主要差异。
