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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Erbas D, Soncul H, Turkozkan N, Arioioglu A, Muftugoglu S, Ersoz A

Department of Physiology, Gazi University Medical Faculty, Ankara, Turkey.

Gen Pharmacol. 1995 Dec;26(8):1669-72. doi: 10.1016/0306-3623(95)00027-5.

An experimental comparative study on isolated guinea pig lungs was carried out to determine the effect of selenium added to pulmoplegic solution on ischemic lung preservation. 2. Two different types of solutions (Eurocollins in control group and Eurocollins + selenium 10(-3) M in experimental group) were infused before 3 hr of normothermic ischemia. 3. Tissue malone dialdehyde (MDA) and tissue glutathione (GSH) levels were assessed before the ischemic period, after the ischemia and at the end of reperfusion. Electron microscopic changes were also studied at the end of reperfusion to compare the cellular injury between the groups. 4. Addition of selenium before the ischemic period relatively decreased tissue MDA levels after reperfusion but did not alter tissue GSH levels.

进行了一项关于离体豚鼠肺的实验性比较研究，以确定在肺麻痹溶液中添加硒对缺血性肺保存的影响。2. 在常温缺血3小时前，分别输注两种不同类型的溶液（对照组为Eurocollins溶液，实验组为添加10(-3)M硒的Eurocollins溶液）。3. 在缺血期前、缺血后及再灌注结束时评估组织丙二醛（MDA）和组织谷胱甘肽（GSH）水平。在再灌注结束时还研究了电子显微镜下的变化，以比较两组之间的细胞损伤。4. 在缺血期前添加硒可使再灌注后组织MDA水平相对降低，但不改变组织GSH水平。

Erbas D, Soncul H, Turkozkan N, Arioioglu A, Muftugoglu S, Ersoz A

Department of Physiology, Gazi University Medical Faculty, Ankara, Turkey.

Gen Pharmacol. 1995 Dec;26(8):1669-72. doi: 10.1016/0306-3623(95)00027-5.

An experimental comparative study on isolated guinea pig lungs was carried out to determine the effect of selenium added to pulmoplegic solution on ischemic lung preservation. 2. Two different types of solutions (Eurocollins in control group and Eurocollins + selenium 10(-3) M in experimental group) were infused before 3 hr of normothermic ischemia. 3. Tissue malone dialdehyde (MDA) and tissue glutathione (GSH) levels were assessed before the ischemic period, after the ischemia and at the end of reperfusion. Electron microscopic changes were also studied at the end of reperfusion to compare the cellular injury between the groups. 4. Addition of selenium before the ischemic period relatively decreased tissue MDA levels after reperfusion but did not alter tissue GSH levels.

进行了一项关于离体豚鼠肺的实验性比较研究，以确定在肺麻痹溶液中添加硒对缺血性肺保存的影响。2. 在常温缺血3小时前，分别输注两种不同类型的溶液（对照组为Eurocollins溶液，实验组为添加10(-3)M硒的Eurocollins溶液）。3. 在缺血期前、缺血后及再灌注结束时评估组织丙二醛（MDA）和组织谷胱甘肽（GSH）水平。在再灌注结束时还研究了电子显微镜下的变化，以比较两组之间的细胞损伤。4. 在缺血期前添加硒可使再灌注后组织MDA水平相对降低，但不改变组织GSH水平。