Amrani M, Schoevaerdts J C, Rubay J, Verhelst R, Eucher P, Bruneau M, Piret V, Kremer R, Dion R
Catholic University of Louvain, Department of Cardiovascular Surgery and Cardiology, Saint-Luc Hospital, Brussels, Belgium.
Cardiovasc Surg. 1995 Dec;3(6):579-81. doi: 10.1016/0967-2109(96)82850-x.
During the period 1970-1993, 116 patients (63 men, 53 women) with native aortic valvular infective endocarditis were treated surgically. The mean age was 37 years. The main causative organisms were streptococci and staphylococci. Indication for surgery was cardiac failure (70 cases), uncontrolled sepsis (30), peripheral emboli (11) and overwhelming destruction of the aortic valve (five). Hospital and late mortality rates were 8% and 11% respectively. Patients who died in hospital and those who presented a paravalvular leakage had a ring abscess associated with aortic wall destruction. Among 34 patients screened for cerebral septic emboli the condition was confirmed in 15, of whom six were symptom-free. Thus, it is believed that in the presence of root abscess, surgery should be undertaken promptly, regardless of the cardiac status. It is confirmed that cerebral septic emboli should be systematically screened for in the presence of any infective endocarditis.
在1970年至1993年期间，116例（63例男性，53例女性）原发性主动脉瓣感染性心内膜炎患者接受了手术治疗。平均年龄为37岁。主要致病微生物为链球菌和葡萄球菌。手术指征为心力衰竭（70例）、无法控制的败血症（30例）、外周栓塞（11例）和主动脉瓣严重破坏（5例）。住院死亡率和晚期死亡率分别为8%和11%。在医院死亡的患者以及出现瓣周漏的患者均有与主动脉壁破坏相关的瓣环脓肿。在34例接受脑脓毒性栓塞筛查的患者中，15例得到确诊，其中6例无症状。因此，据信在存在根部脓肿的情况下，无论心脏状况如何，均应立即进行手术。已证实，在任何感染性心内膜炎患者中均应系统地筛查脑脓毒性栓塞。
