Schoultz T W
J Neurol Sci. 1977 Jun;32(2):283-95. doi: 10.1016/0022-510x(77)90243-x.
The progressive histopathological sequence over the first 3 hr after a 400 g-cm blunt injury to the spinal cord of catecholamine (CA)-intact and CA-depleted cats is described. Norepinephrine levels were measured in all animals. The experiments were designed to determine the role of CA in progressive hemorrhagic necrosis of the spinal cord by removing CA from one group of animals prior to trauma. A second group of CA-intact animals was subjected to identical experimentally-induced trauma. Upon analysis of the histopathological changes, it appears that the sequential nature of the development of hemorrhagic necrosis is both qualitatively and quantitatively similar in both experimental groups. The general conclusion is drawn that catecholamines in greater than normal amounts are present at the lesion site after trauma, but these catecholamines are probably not involved in the process of central hemorrhagic necrosis.
描述了对儿茶酚胺（CA）完整和CA耗竭的猫脊髓进行400 g-cm钝性损伤后最初3小时内进行性组织病理学变化序列。测量了所有动物的去甲肾上腺素水平。实验旨在通过在创伤前从一组动物中去除CA来确定CA在脊髓进行性出血性坏死中的作用。第二组CA完整的动物遭受相同的实验性诱导创伤。通过对组织病理学变化的分析，似乎两个实验组出血性坏死发展的顺序性质在质量和数量上都是相似的。得出的一般结论是，创伤后病变部位存在高于正常量的儿茶酚胺，但这些儿茶酚胺可能不参与中枢出血性坏死过程。
