Wang F, Shi C
First Affiliated Hospital, Third Military Medical College, Chongqing.
Zhonghua Fu Chan Ke Za Zhi. 1995 Oct;30(10):588-90.
To determine the concentration of secretory immunoglobulin A (SIgA) in human milk at 1, 2, 3 and 4 months after delivery and in infants' feces in the same period and find out the effect of milk on the content of SIgA in infants' intestine.
20 women and 12 breast feeding infants and 13 formula feeding infants were studied, and milk and infants' feces were collected at 1, 2, 3 and 4 months after delivery, respectively. The concentrations of SIgA in milk and feces were determined by radioimmunoassay.
No apparent changes in the concentration of SIgA were found in human milk and feces from breast feeding and formula feeding infants at 1-4 months after delivery, but the concentration of fecal SIgA in breast feeding infants was significantly higher than that in the formula feeding infants, during the first 4 months after birth.
Human milk can provide a large amount of SIgA for infants. We conclude from these data that human milk is beneficial in protecting the immunological function of infants digestive tract.
测定产后1、2、3和4个月时人乳中分泌型免疫球蛋白A（SIgA）的浓度以及同期婴儿粪便中SIgA的浓度，并探究母乳对婴儿肠道中SIgA含量的影响。
对20名女性、12名母乳喂养婴儿和13名配方奶喂养婴儿进行研究，分别在产后1、2、3和4个月收集母乳和婴儿粪便。采用放射免疫分析法测定母乳和粪便中SIgA的浓度。
产后1 - 4个月，母乳喂养和配方奶喂养婴儿的母乳和粪便中SIgA浓度均无明显变化，但在出生后的前4个月，母乳喂养婴儿粪便中SIgA的浓度显著高于配方奶喂养婴儿。
母乳可为婴儿提供大量SIgA。从这些数据我们得出结论，母乳有利于保护婴儿消化道的免疫功能。
