Chrétien J
Service de Radiologie Ostéo-articulaire, Hôpital Lariboisière, Paris.
Ann Radiol (Paris). 1995;38(4):169-76.
Paget's disease, often an incidental finding, sometimes presents in the form of pain or signs of complications, such as spinal cord compression, malignant transformation or fissures. The diagnosis is established by laboratory tests, but essentially by radiological findings, based on three basic criteria: cortical thickening, loss of cortico-cancellous differentiation and enlargement of the bone, which deformity is a later sign. The diagnosis can usually be made on plain x-rays, but CT is useful in the case of early, difficult or unusual lesions and complications. CT can reveal mouth-eaten, vacuolar, network, clumped or mixed, fibrillary or ivory images. MRI is a last resort examination. Angioma, metastases and ivory vertebrae are the main differential diagnoses.
佩吉特病通常为偶然发现,有时会表现为疼痛或并发症迹象,如脊髓受压、恶性转化或骨裂。诊断通过实验室检查确立,但本质上基于放射学表现,依据三个基本标准:皮质增厚、皮质-松质骨分界消失及骨骼增大,畸形则是较晚出现的体征。通常通过普通X线片即可做出诊断,但对于早期、复杂或不典型病变及并发症,CT检查很有用。CT可显示虫蚀状、空泡状、网格状、团块状或混合性、纤维状或象牙质样影像。MRI是最后的检查手段。血管瘤、转移瘤和象牙质样椎体是主要的鉴别诊断对象。