Millaire A
Service de cardiologie du Pr Ducloux, CHRU de Lille.
Arch Mal Coeur Vaiss. 1995 Oct;88(10):1453-63.
Ambulatory cardiac radionuclide monitoring is a relatively new technique of non-invasive assessment of left ventricular function. This technique, which uses a portable gamma-ray detector, enables continuous recording over a number of hours of global left ventricular ejection fraction after red cell labelling with technetium. The detector is placed in contact with the skin over the apical region in a 45 degrees left anterior oblique view. Adequate collimation enables the variations in left ventricular volume during the cardiac cycle to be quantified and the ejection fraction to be deduced without having to generate an image. The authors review this method and describe the different available systems. They may be classified in two groups as to whether the technique is limited to continuous bed-side monitoring or if used for ambulatory monitoring (the only commercially available model being the Vest). Validation studies and trials in normal subjects are envisaged. The information acquired by this new method is analysed in the different clinical fields: post-infarction, stable angina, asymptomatic coronary artery disease, hypertension. The role of this new technique in the investigation of coronary artery disease is discussed with respect to other non-invasive techniques. The limitations of the technique and the material are reviewed and possible future developments are described.
动态心脏放射性核素监测是一种相对较新的无创评估左心室功能的技术。该技术使用便携式γ射线探测器，在红细胞用锝标记后，能够连续数小时记录左心室整体射血分数。探测器以45度左前斜位放置在心尖区上方与皮肤接触。适当的准直能够量化心动周期中左心室容积的变化，并在无需生成图像的情况下推导出射血分数。作者回顾了这种方法并描述了不同的可用系统。根据该技术是仅限于连续床边监测还是用于动态监测（唯一可商购的型号是背心式），可将它们分为两组。设想了在正常受试者中的验证研究和试验。通过这种新方法获取的信息在不同临床领域进行了分析：心肌梗死后、稳定型心绞痛、无症状冠状动脉疾病、高血压。就其他无创技术而言，讨论了这种新技术在冠状动脉疾病研究中的作用。回顾了该技术和设备的局限性，并描述了可能的未来发展。
