Etienne G, Révolte X, Lagrange O, Fond B, Belin P
Clinique Saint-Joseph, Angoulême.
Rev Pneumol Clin. 1995;51(5):280-3.
A 65 old man had a solitary primary pulmonary plasmacytoma. Serum immunoelectrophoresis revealed an immunoglobulin G Lambda M-protein. Screening for multiple myeloma with bone marrow biopsy and skeletal survey were negative. The patient underwent left lower lobectomy associated with resection of mediastinal lymph nodes. Immunoperoxydase staining of the mass revealed a monoclonal plasma cell population producing IgG, Lambda chains. No adjuvant chemotherapy or radiation therapy was performed. In few weeks, the paraprotein durably disappeared. Four years later, the patient is well and has no evidence of recurrence or myelomatosis. Authors emphasize the rarity of this tumor. The best treatment of pulmonary plasmacytoma is discussed.
一名65岁男性患有孤立性原发性肺浆细胞瘤。血清免疫电泳显示存在免疫球蛋白G λ型M蛋白。通过骨髓活检和骨骼检查筛查多发性骨髓瘤结果为阴性。该患者接受了左下叶切除术并切除了纵隔淋巴结。肿块的免疫过氧化物酶染色显示为产生IgG、λ链的单克隆浆细胞群。未进行辅助化疗或放疗。几周内,副蛋白持续消失。四年后,患者状况良好,无复发或骨髓瘤病迹象。作者强调了这种肿瘤的罕见性。文中讨论了肺浆细胞瘤的最佳治疗方法。