Bréart G, Rumeau-Rouquette C
Inserm unité 149, Paris, France.
Arch Pediatr. 1996 Jan;3(1):70-4. doi: 10.1016/s0929-693x(96)80013-3.
Actual data on the frequency of cerebral palsy (CP) and "infirmité motrice cérébrale" (IMC), and their relationship with perinatal asphyxia and perinatal managements, are presented. In France, the frequency of IMC at 9 years of age, approximates 1 per thousand, for the 1972, 1976, 1981 generations. Three surveys, two English and one Australian, show an association between perinatal asphyxia and CP. However computation of percent attributable risk indicates that asphyxia can explain only one case of CP out of six among term neonates. These surveys show also that 10% of CP only could be prevented by improving perinatal managements. This, in addition to other factors such as the increase in survival of very preterm babies, explains the absence of a significant reduction of CP frequency despite improvements in the perinatal care.
本文呈现了关于脑瘫(CP)和“大脑运动功能障碍”(IMC)的发生率及其与围产期窒息和围产期管理之间关系的实际数据。在法国,1972年、1976年、1981年出生队列中9岁儿童的IMC发生率约为千分之一。两项英文和一项澳大利亚的调查显示围产期窒息与CP之间存在关联。然而,归因风险百分比的计算表明,窒息仅能解释足月儿中六分之一的CP病例。这些调查还表明,通过改善围产期管理仅能预防10%的CP。这一点,再加上其他因素,如极早产儿存活率的提高,解释了尽管围产期护理有所改善,但CP发生率并未显著降低的原因。