Dhar S, Sharma V K
Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Br J Dermatol. 1996 Jan;134(1):156-8.
We describe seven patients with fixed drug eruption (FDE) due to ciprofloxacin, five confirmed by rechallenge. These cases make up 8.75% of all cases of FDE seen by us during 1992-93. Isolated, and striking involvement of the lips was seen in two patients. To our knowledge, only a single case of FDE to ciprofloxacin previously has been reported. Our experience suggests that, with widespread use, ciprofloxacin could become one of the common drugs causing FDE.
我们描述了7例因环丙沙星引起的固定性药疹(FDE)患者,其中5例经激发试验确诊。这些病例占我们在1992 - 1993年期间所见所有FDE病例的8.75%。两名患者出现了孤立且明显的唇部受累。据我们所知,此前仅报道过1例环丙沙星引起的FDE。我们的经验表明,随着环丙沙星的广泛使用,它可能会成为引起FDE的常见药物之一。