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[反应性噬血细胞综合征:重症监护患者血小板减少症一个可能被低估的病因]

[Reactive hemophagocytic syndrome: a probably underestimated cause of thrombocytopenia in intensive acre patients].

作者信息

François B, Trimoreau F, Vignon P, Verger G, Gastinne H

机构信息

Service de Réanimation polyvalente, CHU Dupuytren, Limoges.

出版信息

Ann Fr Anesth Reanim. 1995;14(6):514-6. doi: 10.1016/s0750-7658(05)80495-2.

DOI:10.1016/s0750-7658(05)80495-2
PMID:8745978
Abstract

Thrombocytopenia is a common feature in ICU patients which occurs usually in case of infection or septic shock. Its mechanisms, which are often unclear, include the haemophagocytic syndrome initially linked with histiocytic proliferation but probably also associated with infectious diseases. This syndrome is characterized by a phagocytosis of medullar blood cells. Reactive haemophagocytic syndrome can probably lead to thrombocytopenia in ICU patients as in this case report of a E. Coli infection.

摘要

血小板减少症是重症监护病房(ICU)患者的常见特征,通常发生在感染或脓毒性休克的情况下。其机制往往不明,包括最初与组织细胞增殖有关但可能也与传染病相关的噬血细胞综合征。该综合征的特征是骨髓血细胞的吞噬作用。如本例大肠杆菌感染报告所示,反应性噬血细胞综合征可能导致ICU患者出现血小板减少症。

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