Kawamura T, Fukuda S, Ohtake N, Furue M, Tamaki K
Department of Dermatology, Yamanishi Medical University, Japan.
Br J Dermatol. 1996 Feb;134(2):358-60.
We report a patient who had lichen planus-like lesions on sites repeatedly exposed to methacrylic acid esters used in the car industry. Histologically, the lesions showed all the features of classical lichen planus. Patch testing revealed positive reactions to methacrylic acid esters in concentrations as low as 5 x 10(-3)%. As dental devices contain methacrylic acid esters, it is possible to speculate that methacrylic acid esters may be one of the causative agents for oral lichen planus.
我们报告了一名患者,其在反复接触汽车工业中使用的甲基丙烯酸酯的部位出现扁平苔藓样病变。组织学上,这些病变表现出经典扁平苔藓的所有特征。斑贴试验显示,对浓度低至5×10(-3)%的甲基丙烯酸酯有阳性反应。由于牙科器械含有甲基丙烯酸酯,因此可以推测甲基丙烯酸酯可能是口腔扁平苔藓的致病因素之一。