Beckmann S, Schartl M, Bocksch W, Fleck E
Department of Cardiology and Angiology, Virchow-Klinikum, HU Berlin, Germany.
Eur Heart J. 1995 Oct;16 Suppl J:10-8. doi: 10.1093/eurheartj/16.suppl_j.10.
Stress echocardiography is being used more commonly for routine clinical diagnosis of coronary artery disease. In addition to physical treadmill or bicycle exercise echocardiography, pharmacological stress echocardiography with dobutamine and dipyridamole has also gained increasing significance over the past few years. Numerous studies have proven that these methods diagnose coronary artery disease accurately (exercise echocardiography: sensitivity 71 to 98%, specificity 64 to 100%, dobutamine echocardiography; sensitivity 54 to 96%, specificity 66 to 95%; dipyridamole echocardiography: sensitivity 57 to 74%, specificity 80 to 100%), but no direct comparison has hitherto been able to prove the superiority of any one of these protocols. However it is recognized that the skill and experience of the echocardiographer performing this study has an influence on the accuracy of the technique.
负荷超声心动图在冠状动脉疾病的常规临床诊断中应用越来越普遍。除了运动平板或踏车运动超声心动图外,在过去几年中,使用多巴酚丁胺和双嘧达莫的药物负荷超声心动图也变得越来越重要。大量研究证明,这些方法能准确诊断冠状动脉疾病(运动超声心动图:敏感性71%至98%,特异性64%至100%;多巴酚丁胺超声心动图:敏感性54%至96%,特异性66%至95%;双嘧达莫超声心动图:敏感性57%至74%,特异性80%至100%),但迄今为止,尚无直接比较能够证明这些方案中任何一种的优越性。然而,人们认识到,进行这项研究的超声心动图检查人员的技术和经验会影响该技术的准确性。